UPDATED 5-26-20
There is increasing evidence that COVID-19 isn’t your typical virus. Thankfully many researchers, scientists, and doctors are observing trends that are changing the way we are treating it in hospitals and at home.
I should be writing this at the beginning of all my articles in the last month but due to the fact that we are all living in real-time and the information coming out is changing moment by moment, even the best scientist’s theories on how to combat this illness continue to evolve. Although things could certainly change as larger studies come forth, for the moment I wanted to share with you some exciting new details that are emerging theories, which could affect future treatment development.
Current Theory and Treatment for Coronavirus
Currently, COVID-19 is being treated as a dysfunction of the lower respiratory tract. It’s primary symptoms are:1
- Fever
- Cough
- Shortness of breath
Interestingly, a large number of COVID-19 patients also report a loss of taste and smell. In mild cases of COVID-19, the virus will run its course and resolve on its own. But if this disease progresses to a critical level, patients spiral into a state of severe hypoxemia – where the body is unable to effectively deliver life-sustaining oxygen to the rest of the body. Without adequate oxygen delivery, vital organs and tissues are starved of oxygen and begin shutting down – which can eventually lead to death.
The current treatments assume that coronavirus is causing a build-up of liquid (instead of air) in the alveoli – making it difficult for oxygen to transfer through the fluid and make its way into the bloodstream. To counteract oxygen deprivation caused by this build-up of fluid, COVID-19 is currently being treated as a case of acute respiratory distress, also known as ARDS. The standard treatment for ARDS is mechanical ventilation – which will force air into the alveoli in hopes of transferring oxygen into the blood.
The problem is, treating COVID-19 with ventilation isn’t working as it should. In fact, some doctors have observed that the use of ventilators may even be harming some patients. So that brings up the question – what if our current understanding of COVID-19 is wrong?
Emerging ideas on the virus…
There is mounting evidence suggesting that our initial understanding of exactly how coronavirus impacts the body may be incorrect.
Consider these mysteries of COVID-19:
- Patients are showing blood oxygen levels so low that they should be life-threatening, but without showing the typical signs of distress that are expected when the same levels are reached due to lung dysfunction.2
- Doctors are saying that ventilators aren’t working as well as they should be and may even be harming some people.2
- Many patients report a loss of taste and smell, typically associated with zinc deficiency, not a respiratory disease.
- Researchers have noted that the pathological mechanism that causes the damage to the body remains a mystery.3
- Twenty percent of COVID-19 patients have cardiac damage.4
- Fatality rates, even among places with robust testing in place, are wildly different.
These discrepancies have hinted at a new culprit as well as new possible solutions. So, should we be treating COVID-19 differently? To answer that question, first, let’s look at exactly how a healthy body is designed to deliver oxygen to your tissues.
How Our Cells Are Designed Carry Oxygen
As you inhale air, oxygen enters your lungs and reaches the alveoli which are lined with a layer of cells that creates the barrier between your lungs and your bloodstream. Oxygen molecules pass through this barrier and attach themselves to a protein called hemoglobin that is bound to your red blood cells. Once your red blood cells have picked up oxygen, they set off to begin delivering it to the rest of the tissues in your body.
Think of your red blood cells like little rafts that are responsible for picking up oxygen and carrying it to your tissues which rely on oxygen for survival. And think of hemoglobin like people on the raft working as a delivery crew – tasked with receiving, holding, and dropping off oxygen molecules. Without the “delivery crew” of hemoglobin proteins, the raft is useless.
It’s also important to understand a little more about the structure of hemoglobin. A vital component of hemoglobin proteins are heme groups – which are embedded in the hemoglobin and are responsible for binding and releasing oxygen molecules. These heme groups are a metal complex and contain iron as the central metal atom, with each iron molecule capable of carrying one oxygen molecule.5 These iron-rich heme groups are critical – without them, your cells are unable to transport the oxygen your tissues depend on.
This understanding the body carries oxygen has sparked speculation about how COVID-19 may be exerting its devastating effects by creating more reactive oxygen species causing tissue damage and hypoxia.
A New Theory on COVID-19’s Mechanism of Injury
One of the most puzzling aspects of COVID-19 is that despite fitting most of the criteria under the definition of acute respiratory failure there is one glaring contradiction. With the coronavirus, there appears to be hypoxia or low oxygen saturation in the blood rather than respiratory distress as seen in classic respiratory failure. Meaning many patients present with severe hypoxia with nearly normal respiratory function.6 This remarkable combination is almost never seen in severe cases of ARDS.
Interestingly, it may be creating a clinical picture similar to someone suffering from severe malaria or altitude illness.
Could COVID-19 Be affecting Oxygen Carrying Capacity?
In COVID-19’s final and severe stages, the lungs are severely damaged. But new information on this virus’s cellular process in the body is revealing that the final condition of the lungs and accompanying respiratory failure may actually be more of a case of massive oxidative stress overload disrupting the capacity of hemoglobin to carry oxygen to tissues rather than an outright attack on the air sacs in the lungs.
The theory on coronavirus affecting the blood’s oxygen-carrying capacity is related to the fact that increased intracellular oxidative stress is at the core of all pathogenic infections. This is often referred to as an increase in reactive oxygen species or ROS. This ROS production is at the core of much of the damage we are seeing not only to the blood’s ability to deliver oxygen to the tissues, causing severe hypoxia or low oxygen but also damaging all tissues they come in contact with. As Integrative and functional medicine doctors, we often measure markers of oxidative stress in our patient’s urine to determine if this process is out of control. One such marker is lipid peroxides. According to Dr. Tom Levy the intracellular levels of Vitamin C, magnesium and glutathione largely affect the oxidative stress which could damage the tissues, one reason why you are seeing Vitamin C being used in hospitals to treat the virus. Stay tuned as I will be writing more about Vitamin C in upcoming blog articles.
This cascade of events would explain:
- Why as many as one in five COVID-19 patients has cardiac damage.
- Why IV nutrients that target cardiovascular function are beneficial.
- Why many people experience a loss of taste and smell.
- Why anti-malarial medications are showing promising results.
This would also explain why ventilators aren’t working quite as we’d expect. Ventilators work by forcing more air into the lungs, so more oxygen can be delivered to the blood. This is helpful when there’s liquid or inflammation in the lungs, and the blood is working normally – like in pneumonia. However, if there is an issue due to the fact that oxidative stress (ROS) has altered the blood’s ability to properly carry this oxygen, then a ventilator can’t do its job. Right now, the Journal of the American Medical Association indicates that COVID-19 patients are candidates for “early, invasive ventilation”. But if we’re ventilating patients who are struggling to keep their little oxygen boats afloat in the bloodstream due to massive oxidative stress, ventilation will do little good and could even cause damage.8
This theory would also give us some more insight as to why certain populations may be more at risk of contracting COVID-19.
This Might Explain Why Anti-malarial Medications Were Being Considered for Treatment.
Hydroxychloroquine, also known as Plaquenil, is an anti-malarial medication that is showing promise as a potential treatment for COVID-19. If coronavirus is in fact attacking red blood cells, similar to the way malaria does, then it would make sense why an anti-malarial drug would be beneficial for coronavirus patients. But how exactly could hydroxychloroquine be exerting these antiviral effects?
Research is finding that it might be due to hydroxychloroquine’s relationship with the mineral zinc. You see, hydroxychloroquine is a zinc ionophore – meaning it enhances your body’s ability to allow zinc into your cells.9 When intracellular concentrations of zinc are increased, it displays broad-spectrum antiviral activity in a few ways:
- Zinc inhibits the actions of certain proteins necessary for the completion of different phases of the virus’s life cycle – essentially halting its ability to reproduce10
- Zinc supports a robust immune response by aiding in the production of cytokines and the modulation of immune cells10
- Zinc acts as a powerful antioxidant and prooxidant – neutralizing the oxidative stress caused by the toxic overload of iron that has been dumped into the blood from the burst cells11,12
Interestingly, one of the initial symptoms reported by many coronavirus patients is a loss of taste and smell. This lack of taste and smell can be caused by a zinc deficiency. Perhaps the action of hydroxychloroquine helping zinc enter cells is part of the reason the drug has benefitted some COVID-19 patients.13 It’s important to note that in order for hydroxychloroquine to work, there must be adequate zinc levels available to allow into the cells – so hydroxychloroquine must be administered in conjunction with zinc to be most effective against COVID-19.
Hydroxychloroquine has shown promise (as well as a risk of severe cardiac arrhythmia in certain patients) but the way the drug functions has given us some powerful insights and may give us answers into how we can save more lives.
The Connection Between COVID-19 and Altitude Sickness
Another interesting connection is the fact that COVID-19’s clinical presentation is quite similar to another respiratory illness – high altitude pulmonary edema, also known as altitude sickness. In both COVID-19 and high altitude pulmonary edema clinical findings include:14
- A decreased ratio of arterial oxygen levels to inspired oxygen
- Hypoxia (low oxygen levels) and tachypnea (abnormally rapid breathing)
- Low carbon dioxide levels
- A ground-glass appearance in the lung tissues
- Elevated fibrinogen levels
- Diffuse alveolar damage
In altitude sickness, the lungs are functioning fine – there are just inadequate levels of oxygen to process to properly meet the needs of the body. Clinical findings similar to altitude sickness would make sense if COVID-19 is in fact causing dysfunction of red blood cells through the production of massive oxidative stress rather than a direct problem with the lungs.
So What Are Potential Options to Quench Oxidative Stress?
Even with all of the information that points to COVID-19 creating massive oxidative stress, there are still a lot of unknowns. The downside of this is, of course, the trial and error and continued research that needs to take place before we have real answers. The upside is that this information gives us an array of new potential options to consider:
High Dose Vitamin C:
High doses of vitamin C are garnering attention as a powerful way to potentially mitigate the effects of coronavirus. These ultra-high doses of vitamin C are speculated to fight the massive immune response and subsequent respiratory failure seen in coronavirus infection by: 15,16
- Suppressing the over-reactive inflammatory response in the lungs
- Minimizing the accumulation of immune cells in the tissues of the lungs
- Decreasing the release of cytokines (chemical messengers involved in the immune response)
- Slowing down the viruses ability to reproduce and spread
- Neutralizing the oxidative stress caused by the massive amounts of iron floating around in the bloodstream
Ideally, high dose vitamin C can be delivered intravenously, where it is more easily absorbed and utilized intracellularly. But oral vitamin C can also be beneficial if taken correctly. While regular over the counter oral vitamin C causes diarrhea, liposomal Vitamin C at frequent intervals does not, and is an effective way to increase intracellular levels. Several New York hospitals have approved intravenous vitamin C as a therapy for the first time ever in studies being conducted on the virus.
Glutathione:
Glutathione is a potent antioxidant naturally found in most of the cells in your body. Glutathione plays a few major roles in immune function including:
- Functioning as a signaling molecule – helping balance inflammation levels and modulating immune system response17
- Reducing oxidative injury by neutralizing harmful toxins 18
- Regulating cellular proliferation and apoptosis19
There is a growing mountain of evidence finding that the most effective way to take glutathione may be through inhalation. Inhaled glutathione (aerosolized or nebulized) is already being used in the treatment of a variety of respiratory-related conditions.
Inhaled Hydrogen:
The inhalation of concentrated hydrogen gas is another powerful antioxidant. Inhaling hydrogen gas has been found to: 21,22
- Reduce oxidative-stress induced damage
- Reduce cellular apoptosis
- Improve gas exchange in the lungs
- Block the production of proinflammatory mediators
Inhaled hydrogen gas may be particularly effective when paired with other anti-oxidative therapies such as IV vitamin C and inhaled glutathione.
Other Antiviral Drugs:
A number of other antiviral medications are being studied. These include:
- Methylene Blue: Methylene Blue is a medication that has been used in the treatment of malaria due to its powerful antiviral properties – killing the virus at an impressive speed.23 It’s also used in the treatment of a condition known as methemoglobinemia – a condition in which individuals have too much methemoglobin which is a form of hemoglobin that is much less effective at carrying oxygen. Methylene blue works by converting methemoglobin into a type of hemoglobin that can more effectively transport oxygen.24
- Remdesivir: Remdesivir is another antiviral drug used for Ebola. Remdesivir is showing benefit in solid studies – a small but well-conducted study on severe cases in the US, Canada, Europe, and Japan concluded that Remdesvir caused clinical improvement in 68% of patients.25
- Favipiravir: Favipiravir is a powerful anti-viral agent that inhibits the virus from replicating and spreading.26 It has been approved in China and Japan for the treatment of influenza and is undergoing research to determine its potential efficacy in treating COVID-19.27
Hyperbaric Treatment:
Hyperbaric treatment works in two ways. First, the oxygen concentration is increased to nearly 100%. Secondly, ambient pressure is increased to about three times higher than the air pressure we normally breathe. This combination is designed to essential “hyper oxygenate” your blood – improving oxygen delivery to your tissues.28
Let's band together…
There are still many unknowns when it comes to coronavirus. The only thing we know for certain is that we are in a race against time. I hope we will continue to search for clues and change course when wrong.
I urge my fellow clinicians and researchers to examine this virus and its mechanism of action with fresh eyes. We entered into this field knowing we were signing up for being lifetime students. This current pandemic is calling us to rise to the occasion – the world is counting on us all to band together to find answers.
In compliance with FTC guidelines, I am not selling (nor have I ever sold) the products or services listed in this article, including hyperbaric oxygen therapy, high dose IV Vitamin C, inhaled glutathione, or inhaled H2 therapy.
References:
- https://www.cdc.gov/coronavirus/2019-ncov/about/symptoms.html
- https://www.statnews.com/2020/04/08/doctors-say-ventilators-overused-for-covid-19/
- https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173
- https://khn.org/news/mysterious-heart-damage-not-just-lung-troubles-befalling-covid-19-patients/
- http://www.chemistry.wustl.edu/~edudev/LabTutorials/hemoglobin.htm
- https://www.esicm.org/wp-content/uploads/2020/04/684_author-proof.pdf
- https://link.springer.com/article/10.1007/s00109-008-0368-5
- https://jamanetwork.com/journals/jama/fullarticle/2762996
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/
- https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus
- https://www.hindawi.com/journals/omcl/2018/9156285/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488004/
- https://link.springer.com/chapter/10.1007/978-4-431-68120-5_2
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096066/
- https://clinicaltrials.gov/ct2/show/NCT04264533
- https://www.sciencedirect.com/science/article/pii/S0033062020300372?fbclid=IwAR0UMWXFiQvxpIBxCOvg8zpFQLBgq8zTUmI5LOc-HDd0G32SzeBbcv9cFz0#bb0070
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048347/
- https://www.ncbi.nlm.nih.gov/pubmed/19393193
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/4
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249747/
- https://www.researchgate.net/publication/47676317_Inhaled_Hydrogen_Gas_Therapy_for_Prevention_of_Lung_Transplant-Induced_IschemiaReperfusion_Injury_in_Rats
- https://www.ncbi.nlm.nih.gov/pubmed/23852510
- https://www.sciencedaily.com/releases/2018/02/180205195624.htm
- https://www.drugs.com/mtm/methylene-blue-injection.html
- https://www.nejm.org/doi/full/10.1056/NEJMoa2007016
- https://www.ncbi.nlm.nih.gov/pubmed/28769016
- https://www.jwatch.org/na51293/2020/04/09/favipiravir-potential-antiviral-covid-19
- https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/hyperbaric-oxygen-therapy
The information in this article is not intended to diagnose, treat, cure, or prevent any disease state or medical condition and has not been evaluated by the <a href="https://www.fda.gov/" target="_blank" rel="noopener noreferrer">FDA</a>. This is not intended to replace any recommendations by or relationship with your physician. The references included in each article allude to the level of scientific rigor I have applied to my writing. When changes become apparent we will update the information if appropriate.
53 Comments
This information makes some sense to me. I have also been reading about the blood type could play another factor in diagnosing Covid-19. I have the book by Dr. D’Amato called “You are what your blood type”. I have referred to his book many times to what foods that are like good medicine for me, foods that are neutral and foods that are like poison according to the blood type. The current literature I have read say the people with blood type 0 do not get as ill as blood type A people and that some 0 type blood people are exposed to Covid- 19 that test negative. Could this be due to not having the antigens in 0 type blood?
The zinc introduction makes sense too.
It is interesting that some people are harmed by ventilators.
Thanks for your summary of the possibility to a thoughtful paradigm shift in where to look for some other venues of cause and effect.
I am going to keep your information because I follow a path of shifting by using other mechanisms into making summaries of conclusions.
Cheryl
Wow, Dr. Jill, thank you! It’s the first time I’ve seen such logical explanations and recommendations. I’ve been reading your work for years and will share this with everyone I know.
Wow Dr Carnagan, this was a super interesting article! Thank you!
The Ivs treatments are defiantly for clinics, but can we get these treatments at home? Specially the Inhaled glutathione (aerosolized or nebulized) ?????
Thank you for sharing such a great information!
Also a question, I watched a video of you talking about how vegetarian life style was killing you and caused you to develop cancer, and I was surprised to hear that, so how we can tell if the life style or the diet we are choosing is the right for us and our children in specific.
Thanks again.
Liposomal C in frequent doses may equally raise intracellular Vitamin C levels
An inciteful article. Thank you for this. I have listened to Dr. Klinghardt who mentioned the elevated presence of Iron as a blood marker to look out for and also depletion of Zinc. So the puzzle pieces are coming together.
Jill: thank you for this theory, and this article. Your ideas make sense. Perhaps a blood transfusion helps too. I am also an integrative and functional medicine coach in México City, and I wrote a 10 points guide for the use of an antiviral available, and I made a translation into English due to the importance to know this info by the must hitted places in the world, including USA. You can hear it in my youtube. I finished yesterday another coach specifically for heart issues related to covid19, in Spanish, and you can read it in the google doc that I will post in the text of the vídeo related to the antiviral. I will add a link to your article too, if you agree, and God allows me to. Maybe this completes the vision for good at last.
Iván Ardila, islamic health coach:
http://www.youtube.com/ivanardila
Thank you Ivan – I doubt blood transfusions would help as this would add more iron to the body when what is really needed is anti-oxidants which can quench the ROS that occurs from the infection
It seems logical that transfusion support, with administration of blood or packed red blood cells, would be helpful to replenish hemoglobin that has been ruptured by the virus and can no longer transport oxygen. Maybe along with Vitamin C and Zinc?
While it sounds logical, these are theories and due to other issues such as hypercoagulablity or increase risk of clotting I am not sure there is any evidence this would be safe or effective
Dr Mike Hansen’s video on YouTube “Why Some People Die” seems to debunk the heme factor (near the end of the video). So confusing.
I think the issue is more related to massive oxidative stress created by the virus vs. the virus directly attacking heme groups. But time will tell what theories become reality…
Great article. Thanks for sharing. 10 pass IV or rectal / ear insufflation of ozone can indeed be a great tool to treat viruses, but inhaling ozone gas is dangerous. You may want to revise this statement: “Nasal Ozone: Inhaling ozone gas helps your body more effectively uptake oxygen and activates a healthy immune response.” For clarification or more info on using ozone therapeutically, you may want to get in touch with Dr. Robert Rowan. I would hate for someone to read this article and accidentally harm themselves.
https://www.nih.gov/news-events/nih-research-matters/how-ozone-harms-lungs
Yes, of course, John! Thank you for clarifying – I was referring to nasal insufflation, NOT inhalation.
warmly
Dr Jill
Dr. Jill,
This is by far the most comprehensive synthesis I’ve seen anywhere. Thank you for all the research you did pulling it together. One thing you’ve added that I haven’t seen before: zinc deficiency producing loss of smell and taste. Brilliant!
Now, how do we get the medical community to widely use IV high-dose vitamin C–when there aren’t Pharma reps to push it? I fear the media’s hyper-focus on a vaccine has distracted medicine from the low-cost treatments you’ve listed, because they won’t produce the outsize profits Pharma seeks.
Dr Jill, thank you for that article. I believe you are correct that it’s a disease attacking the RBC. Do you think it is a good time to take ferritin? Would that carry the free iron? Also, for a person with no spleen there is all that RBC debris floating in the blood. Do you have any thoughts on what that will do to a person with the virus?
In the end someone makes sense! Thank you.
As far as using the treatment options, what would you recommend that people do? I am in Toronto, Ontario for example and I have no idea what to do/where to go once diagnosed (or a loved one) with this virus. Obviously, hospital is of no help.
I am looking forward to your response.
Thank you!
Alina: if you are in Toronto, and you or a loved one gets sick, especially if found to be COVID positive, then the hospital is exACTLY where you should go! Contact your PCP, contact the hospital and alert them so the front line providers can be optimally prepared. To say that “obviously, hospital is of no help” displays a total lack of understanding of the disease AND the healthcare system.
Excellent information. Makes sense. I’m continuing my Vit C and Zinc!
Very interesting information. On the ozone…you are talking about just ozone pumped into the sinuses or inhalation via an ozone oil bubbler? I’m assuming it might be the latter as you don’t want to get direct ozone into the lungs.
Thanks for all you do!
Mark
Hi will this treatment be helpful for chronic fatigue in ME patients? I’m currently taking zinc, vit C , gluathiane,
Have chronic infection of some sort. High white blood cells and oval shaped red blood cells ? CD57 is low.
Will any of the medications help for this?
yes, any immune supportive therapies could be potentially helpful for chronic fatigue syndrome
Hi, thank you for this. We are presenting very much like HAPE and are fully on board with this theory, which we have been hearing about/researching since Apr 5 or so. Our home is located at 8600’ above Boulder and we have, in the past month since symptom onset, had two failed attempts to return home. We most recently had to retreat back down earlier today. There’s a lot to our story (and even more since today) but I invite you see what I’ve written up here: http://40tribesbackcountry.com/my-covid-experience. Please get in touch if you’d like to inquire any further into our particular case.
thanks for sharing your experience, Ryan!
Great summary. I’ve found clients who have environmentally induced porphyria to be at most risk of adverse outcomes with COVID 19. In particular, majority of clients who have really declined, are those with elevated mobilized Lead(mobilized is the key word), which inhibits ALAD, leading to elevated Porphyrns, dysfunction, particularly in unbound Copper, and unbound Iron resulting in elevated Hydroxls/Fenton reaction to be one of the underlying problems. The treatments so far that has helped the most, have been first binding the lead, copper/iron. That has been a CRITICAL part of the treatment, followed by suppressing the hydroxyls with inhaled hydrogen. Finally, every client with COVID 19 had fungal colonization in their lungs, created mycotoxins internally. I needed to treat the Porphyria and the Fungal/Bacterial colonization in the lungs to quickly stablize clients.
“environmentally induced porphyria” Curious you mention this ‘syndrome’. I’ve used porphyria to help explain my, Herbivore Hypothesis. The increased iron levels cause porphyria to manifest, and they’ve shown porphyria can be controlled by lowering iron levels and not consuming meat. The consumption of heme iron, specifically blood, leads to what has now been coined ‘age-related iron accumulation’.
I have a copy of the National Geographic Desk Reference to Nature’s Medicine. I see that Sweet Wormwood (Artemisia Annua) is extacted under name artemisinin which is available on Amazon is an traditional Chinese anti-malarial medicine. Would this be somthing to buy and have on hand? When would one take this – as a preventative or only after COVID symptoms appear? Please advise.
Hi Christine,
I do not know of any evidence that suggests artemisinin would be effective for treating the virus
warmly
Dr Jill
Are Covid-19 patients ever tested to see what their free iron or hemoglobin levels are? When hemoglobin is altered, would it still show up in a test as hemoglobin? I’m just wondering how these things might be confirmed in patients. Are there more natural zinc ionophores besides drugs, like quercetin that could be as effective, or even taken as a preventative with zinc to make sure your zinc levels are high maybe to keep from having a bad case? I’m sure my questions show all kinds of holes in my understanding, but all of this sounds so promising but we don’t hear anything about it.
Thanks for this well written and informative article!!
Yes, this is all speculation so I think time will tell if there is anything to the theory
Could this theory be tested by giving patients recovering form severe infection a blood transfusion?
No David – that is an interesting idea but more oxygen is needed to tissues not more blood.
Dr Jill, the added oxygen will not be capable of binding to the heme if a virus protein is already there. Increased oxygen may be of some benefit if the patient still has red blood cells, which the virus has not affected yet.
I am wondering that also. Not just a blood transfusion, but an exchange transfusion like they do for sickle cell patients at times. If the virus is attacking the red cells and rendering them incapable of carrying oxygen, a ventilator or added oxygen is not going to help. Exchange transfusion and antivirals?
Very Interesting!
How high a risk for developing COVID 19 complications is someone with MCAS with mold toxins but not other co-morbidities?
Please contact me. I find all of this research insightful and have genetic information to share.
Very intersting. Would it not make sense also to increase the level of zinc in our systems? Was wonderkng why you hadn’t included that on your list along with Vitamin C, etc.
yes, zinc is critical for immune function
My daughter and her husband have this disease, she is almost asymptomatic, he has a cough that, while not horrible is worsening. They eat healthy (semi-vegan), are quite active and have 2 young children living at home. She is a school nurse, he a prison guard. They do not have a primary care physician and are both at home.
I bring them tonic water for the quinine, they take 25 mg of zinc a day.
I think they should increase the zinc. Please confirm, add lipisomal vitamin c, how much? Vitamin d?
If this is the case, it seems that RBC transfusion from a donor who has had COVID and recovered (with antibodies) would make sense as a treatment. Also, artemisinin annua seems as though it would be a homeopathic treatment for those infected.
Dr Jill,
Thanks for your excellently written and vastly thorough article. Please consider the results of researchers at the Sichuan University of Science and Engineering, China, who would also largely agree with your extensive evaluation. They have discovered that Covid-19 produces a protein that then binds to the heme portion of the molecule, thus preventing either oxygen or carbon dioxide from attaching, thereby suffocating the host. Relatives of mine In the medical field have noted that in NY some patients have responded well to Flagyl because it’s theorized that Flagyl produces oxidizers that do two things: 1) disrupts the virus DNA and/or RNA and 2) destroys the vvirus’s binding protein. I recommend that for patients that are already having difficulty breathing, a blood transfusion would introduce unaffected red blood cells into the body. If the patient can no longer breathe properly due to congestion, then oxygenated blood would need to be transfused. Hopefully, this approach will be introduced instead of immediately ventilating patients.
Thank you for your insight, DR. Cucchiara, very thought provoking
Thank you for your article. Dan and I appreciate your work pulling together and clarifying the bits and pieces we are hearing in news and media. You have certainly made the information easily understandable and offered positive remediation! Bravo!
This is extremely important information. Thank you for sharing this information so clearly. I hope other doctors are tuning in to this perspective as well. It is so important that doctors and researchers share such information in an easily-digestible manner, since most of us don’t have the time or the background to be able to sort through all the medical data and research.
I know it is easy to dismiss theories that COVID19 might be somehow related to or exacerbated by 5G technology as “conspiracy theories” and such, but in light of significant evidence that points in that direction, it seems worth looking in to. I was recently led through some information that completely coincides with this new hypothesis you are presenting about the virus, because 5G radiation causes oxygen to spin so fast that our hemoglobin cannot take it up.
Here are some key pieces of evidence. First of all, Wuhan China was the first city in the world where 5G technology was being piloted across a whole city (including in hospitals). The technology went online sometime in the fall of 2019. Apparently, some of the other places hard hit by COVID19 are also the places where 5G technology is already being used. I have not had a chance to research and confirm this extensively yet, but with an initial search I have verified that Italy and New York are among the places where the most 5G technology has been rolled out– you can see this on an industry map, here: https://www.speedtest.net/ookla-5g-map
Importantly, 5G technology uses 60 Ghz frequency. This frequency is well-known among technologists as having (almost) the highest rate of attenuation because of the *high oxygen absorption of the microwaves.* http://www.rfcafe.com/references/electrical/atm-absorption.htm. (Actually, 63 Ghz has the very highest rate of oxygen absorption, but 60 Ghz is clearly very close to that peak). In other words, oxygen in the air absorbs the radiation at a very high rate. (Tech companies like this because it means there won’t be a lot of microwaves from different companies that are overshooting and interfering with each other).
Apparently, when oxygen absorbs this level of microwave radiation, the electrons spin so fast that the hemoglobin has much more difficulty picking it up. Thus, oxygen is not being transferred to the blood in the lungs. It seems this would cause exactly the symptoms and patterns you describe in your article.
In light of all this circumstantial evidence, it seems to make sense to look at 5G technology as a possible factor in the COVID19 deaths. I’m wondering if this has come to your attention yet? If so, I’m curious to know whether you do or do not think there is something worth investigating here?
I have not removed any references or footnotes from original
What do you suggest as a way to get extra vitamin C when the traditional supplements are not tolerated?
you may eat citrus fruits, tomatoes, peppers, broccoli and many other fresh fruits and veggies.
Have you already tried vitamin C as liposomal C, ascorbyl palmitate, or possibly vitamin C ester?
What about nebulized hydrogen peroxide? I am seeing certain functional medicine doctors utilizing this…
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