Immunology in the Gut Mucosa. The gut mucosa hosts the body's largest population of immune cells. Nature Immunology in collaboration with Arkitek Studios have produced an animation unravelling the complexities of mucosal immunology in health and disease….
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The gut mucosa is the largest and most dynamic immunological environment of the body. It's often the first point of pathogen exposure and many microbes use it as a beachhead into the rest of the body. The gut immune system therefore needs to be ready to respond to pathogens but at the same time it is constantly exposed to innocuous environmental antigens, food particles and commensal microflora which need to be tolerated. Misdirected immune responses to harmless antigens are the underlying cause of food allergies and debilitating conditions such as inflammatory bowel disease. This animation introduces the key cells and molecular players involved in gut immunohomeostasis and disease. This award-winning animation introduces the key cells and molecular players involved in gut immunohomeostasis and disease. (From Nature.com)
Animation by Arkitek Scientific.
Produced with support from Janssen Pharmaceutical Companies of Johnson & Johnson. For information from the sponsor, please click here.
Nature has full responsibility for all editorial content, including NatureVideo content. This content is editorially independent of sponsors.
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1 Comment
I didn’t realize that the gut mucosa was often the first point of pathogen exposure. It makes sense why you would want to keep this part of your body healthy. I also didn’t know that it was misdirected immune responses that caused allergies. This was a great video and really helped me to understand the process and how our bodies work. Thanks for sharing!
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