At the core of functional medicine is one guiding principle: get to the root cause. 

For many, that root cause is toxin overload—from mold, heavy metals, pesticides, plastics, and other environmental exposures disrupting immune function, brain health, hormones, and energy. 

More Than Therapeutic Plasma Exchange (TPE)

PlasmaXchange, developed by MDLifespan, is a physician-led, Therapeutic Plasma Exchange (TPE) protocol designed for advanced detoxification and immune reset. MDLifespan—founded by Dr. Paul Savage, an expert in toxin removal—is the nation’s first medical group dedicated exclusively to TPE for environmental detoxification and regenerative wellness.

Now Serving Boulder, Denver, and Nationwide

PlasmaXchange will soon be available at Flatiron Functional Medicine in Boulder, offering convenient access for patients across Boulder, Denver, and the greater Colorado area. Not near Colorado? MDLifespan also offers PlasmaXchange at locations nationwide, with new centers opening regularly.

What sets PlasmaXchange apart?

Personalized Medicine

Every protocol includes TPE plus nutrient IVs, lifestyle guidance, regenerative therapies, and targeted supplements

Sustained Results

A long-term maintenance plan helps prevent future toxin buildup and supports lasting wellness.

Proven Results

Patients have experienced up to 89% reduction in inflammatory markers and over 90% reduction in environmental toxins like PFAS and microplastics. 

PlasmaXchange Protocols include:

  • MDL Brain – Cognitive health
  • MDL Heart – Cardiovascular inflammation
  • MDL Immunity – Immune resilience
  • MDL Longevity – Aging biomarkers
  • MDL Cancer – Immune support in cancer care
  • MDL Baby – Preconception detox
  • MDL Toxin – Comprehensive detox
  • MDL Basic – One-time reset
  • MDL Mold – Coming soon

PlasmaXchange Protocols include:

Download

Download the PlasmaXchange Guide

Schedule

Schedule a Free Physician Consult

Find

Find a Location Near You